Factors leading to infertility

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Infertilty doctors on Jul 02, 2012 Says :

This video shares helpful information about infertility treatment. People who are not able to conceive naturally or having multiple birth problems can read this article and enhance their knowledge. This video is really helpful and provides effective information. http://www.onlineinfertilitytreatments.com/

twinkle rose on May 29, 2012 Says :

valuable

Nordine AL-Rashidy on May 03, 2012 Says :

mor4e than exscelet breife

cumar.me16@hotmail.com on Mar 30, 2012 Says :

I am student for the university of somalia my faculty is ganeral medicine

david on Nov 28, 2011 Says :

good presentation

Isabelle on Oct 17, 2011 Says :

A wonderful job. Super heplufl information.

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Show Notes

Slide 1 :

Infertility facts affects 1 in 6 married couples of childbearing age definition: have engaged in unprotected coitus for 1 year and haven’t become pregnant

Slide 2 :

Infertility Facts can be due to: failure to conceive, loss of conceptus origin of problem: 35% female 35% male 20% both partners 10% unexplained

Slide 3 :

Failure to ovulate often caused by low body fat or stress GnRH surge may be inadequate

Slide 4 :

Tubal blockage Due to: Endometriosis, scar tissue from STD, previous surgery Treatment: surgery If surgery unsuccessful, IVF, GIFT and ZIFT are best options

Slide 5 :

Causes of male infertility low sperm count (oligospermia) or absence of sperm (azoospermia) male may produce antibodies to his own sperm accessory glands / ducts may malfunction

Slide 6 :

Intracervical or intrauterine insemination (ICI / IUI) Artificial insemination definition: sperm introduced into female reproductive tract by means other than coitus (near cervix or in uterus) sperm can come from donor / sperm bank or from husband Example of a sperm bank: http://www.spermbankcalifornia.com/buy-sperm-online.html

Slide 7 :

ICI / IUI, cont’d. usually, several ejaculations are pooled 60,000 babies / year born in US. as result of artificial insemination often used when male has low sperm count or antibodies present in ejaculate

Slide 8 :

In vitro fertilization “test - tube babies” 1st performed in 1978 (Louise Joy Brown) often performed on infertile women with tubal blockage

Slide 9 :

IVF Protocol GnRH agonist (e.g. Lupron) for 7 days FSH agonist (follistim, Gonal-F, Repronex) until follicles measure 17-20 mm in diameter (8-14 days) hCG given to induce egg maturation Egg retrieval (transvaginally) 34-35 h later

Slide 10 :

IVF protocol sperm and ova added to dish; fertilization occurs 12-14hrs. eggs transferred to new dish and cell division occurs embryos squirted into uterus (optimal stage: blastocyst) Preimplantation genetic diagnosis (PGD)

Slide 11 :

IVF Protocol, cont’d. 3 to 5 embryos are injected to increase chances of pregnancy woman given progestagen to prevent miscarriage Example of prices: http://www.advancedfertility.com/ivfprice.htm

Slide 12 :

IVF Protocol, cont’d. new variations / improvements: Intracytoplasmic sperm injection (ICSI) use of frozen embryos 27,000 attempts made per year; 18.6% successful (success rates are increasing) http://www.advancedfertility.com/sampleivfcalendar.htm

Slide 13 :

IVF, cont’d. Ethical questions: will it lead to selective breeding? up to what stage can research be done? if embryo dies in vitro, is it abortion, murder? what should be done w/ unwanted embryos? should government regulate research?

Slide 14 :

GIFT and ZIFT GIFT = gamete intrafallopian transfer useful for tubal blockage ova are collected and inserted into oviducts below point of blockage husband’s sperm are placed in oviduct

Slide 15 :

GIFT and ZIFT woman is treated with hormones to prevent miscarriage 28% successful ZIFT = zygote intrafallopian transfer ZIFT is like IVF, only zygotes (1 cell stage) are inserted below blockage in oviduct (24% success rate)

Slide 16 :

Others Ovarian stimulation protocol Surrogate pregnancy Adoption

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Desc : Infertility facts affects 1 in 6 married couples of childbearing age. failure to conceive, loss of more Infertility facts affects 1 in 6 married couples of childbearing age. failure to conceive, loss of conceptus origin of problem. Infertility problem arises because of many factors which leads to miscarriages and derailed birth related problem. - Slides less