Cholangiocarcinoma


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1 : Dr Nilesh Tulaskar Cholangiocarcinoma
2 : Bile duct anatomy
3 : Definition of Cholangiocarcinoma Cholangiocarcinoma is a rare tumor arising from the biliary epithelium and may occur anywhere along the biliary tree. About two-thirds are located at the hepatic duct bifurcation. (60%-80% of cases ) Most cholangiocarcinomas present with jaundice, and the diagnosis of cholangiocarcinoma should be considered in every patient with obstructive jaundice Surgical resection offers the only chance for cure, however, many patients have advanced disease at the time of diagnosis. Most patients with unresectable disease die within a year of diagnosis.
4 : Incidence The incidence of cholangiocarcinomas increases with age, and the majority of patients are 65 years and older. The peak incidence is in the eighth decade of life and more common in men. Overall, the incidence of cholangiocarcinoma in the United States is approximately 1.0/100 000 people per year
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