Micro Nanotechnology ppt transforming Medical Applications

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Slide 1 :

1 www.tfi-ltd.co.uk Micro & Nanotechnology transforming the Market in Medical Applications Dr J Malcolm Wilkinson Technology For Industry Ltd Cambridgeshire, UK www.tfi-ltd.co.uk

Slide 2 :

2 www.tfi-ltd.co.uk Technology For Industry Bridging the gap between industry and revolutionary technology from academia and research institutes

Slide 3 :

3 www.tfi-ltd.co.uk TFI provide solutions for industry leaders to address their greatest technology challenges and achieve long term growth TFI is the market leader in the medical Micro and Nanotechnology consultancy sector Unrivalled team of experts Independent and effective Produce tailored solutions not ‘one size fits all’

Slide 4 :

4 www.tfi-ltd.co.uk Contents of Presentation Overview of the Market & Market Drivers Technology Push – Hot R&D Topics Drug Discovery Drug Delivery Monitoring & Diagnosis Implanted Devices

Slide 5 :

5 www.tfi-ltd.co.uk Present Major Medical Applications of MNT Cardiovascular Drug delivery & Therapy Genetics Neurology Oncology Point of care diagnostics Surgery Tissue engineering Prostheses Pathology ….but what are the largest or fastest growing markets?

Slide 6 :

6 www.tfi-ltd.co.uk Size of Markets Drugs & Drug Delivery $80 billion Blood Analysis $22 billion Heart Pacemakers & Other Implants $16 billion Endoscopy & MIS Tools $5 billion Hearing Aids $4 billion DNA / Lab on Chip $1.2 billion ….and the MNT based Products account for $7 billion or at the component level about $363 million

Slide 7 :

7 www.tfi-ltd.co.uk Drivers in healthcare Ageing population Personalized health Earlier diagnosis Cost of healthcare Global travel (epidemics) Food safety Monitoring of individuals (glucose, cholesterol) Ethics (eg stem cell research, animal testing)

Slide 8 :

8 www.tfi-ltd.co.uk Hot R&D Topics Lab on Chip Retinal Implants Non Invasive Blood Glucose Monitoring The ‘Electronic Rat’ …but what are realistic timescales?

Slide 9 :

9 www.tfi-ltd.co.uk Timescales? Roadmaps based on current status of R&D Future vision Past experience Balance market drivers against barriers

Slide 10 :

10 www.tfi-ltd.co.uk Drug Discovery & Development

Slide 11 :

11 www.tfi-ltd.co.uk Drug Discovery & Development Process © Dr George Adamson

Slide 12 :

12 www.tfi-ltd.co.uk Drug Discovery & Development Issues How to speed up the process Faster removal of poor candidates from the pipeline Reducing screening costs Reducing the need for animal testing Potential for Micro & Nanotechnology Massively parallel screening Automation of the process Building the ‘electronic rat’

Slide 13 :

13 www.tfi-ltd.co.uk Drug Discovery & Development Caliper DNA Chip Infineon DNA Chip Multi - Chamber BioReactor

Slide 14 :

14 www.tfi-ltd.co.uk Roadmap of MNT in Drug Development Improved understanding of links between genes and disease Improved understanding of drug activity and toxicity

Slide 15 :

15 www.tfi-ltd.co.uk Blood Glucose Monitoring Source: Glucowatch Source: Lein Applied diagnostics Fingerstick Invasive Minimally Invasive Non Invasive

Slide 16 :

16 www.tfi-ltd.co.uk Blood Glucose Monitoring

Slide 17 :

17 www.tfi-ltd.co.uk Drug Delivery MICROPARTS KTH ALZA CORP Micronozzle in nebuliser, Microparts Microneedles development, KTH Stealth technology, lipid nanoparticle, Alza Corp.

Slide 18 :

18 www.tfi-ltd.co.uk Drug Delivery Roadmap for MNT

Slide 19 :

19 www.tfi-ltd.co.uk Implanted Devices pacemakers stents

Slide 20 :

20 www.tfi-ltd.co.uk Implanted Devices Installed base of Implants Worldwide …but cardiovascular stents do not fit this model

Slide 21 :

Today Start feeling sick Get a Doctor’s appointment and wait or go to the ER (and wait) One treatment fits all

Slide 22 :

From Housecalls to House Calls Tomorrow, your house will call the doctor

Slide 23 :

Slide 24 :

24 www.tfi-ltd.co.uk TFI Roadmaps Further Roadmaps, Market Analysis and Technology Trends will be available within next few months. Check www.tfi-ltd.co.uk for further details. TFI ~ Navigating The Nanospace ©

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