New Treatment for Basal Cell Carcinoma

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Slide 1 : New Treatment for Basal Cell Carcinoma The scientists of the world has found a new treatment for the rare skin cancer which is termed as Basal Cell Carcinoma Erivedge (vismodegib) capsule has been developed as an alternate treatment of patients who are suffering from basal cell carcinoma.
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Slide 3 : What is Basal Cell Carcinoma Basal Cell Carcinoma is a rare skin cancer which gradually grows and can be cured by cutting it away. Sometimes, it may occur at such parts of the body where, to conduct a surgery may not be possible.
Slide 4 : Sometimes surgeries may not be an option Basal Cell Carcinoma may spread to several parts of the body making the surgeries for treating cancer, like radiation therapy and chemotherapy impossible for the doctors.
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Slide 7 : Main Act of Erivedge Erivedge is prescribed to be given orally once in a day and considered to be the first Hedgehog pathway inhibitor, which has been approved by the Food and Drug Administartion, recognized to provide a new treatment option for the patients suffering from Basal Cell Carcinoma.
Slide 8 : Availability Erivedge is not available at local pharmacies or drug stores. It is preferably distributed only through specialty pharmacies.
Slide 9 : Side-Effects on Animals If used on animal population, it may have embryotoxic and teratogenic effects. Teratogenic effects may include severe midline defects, missing digits and other irreversible malformations.
Slide 10 : Safety Information There may be a possibility that Erivedge capsule can cause a fatal harm to a pregnant women. Thus, it is advised that a woman must verify her pregnancy status before initiating the use of Erivedge.
Slide 11 : Safety Advise It is advised to the females users of Erivedge that they must make use of contraception during and after the treatment. They must verify their pregnancy status within 7 days after initiating the use of Erivedge.
Slide 12 : Safety Advise Male patients are advised to use condoms or any other mode of contraception while having sexual intercourse with those females who are being treated with Erivedge.
Slide 13 : Safety Advise The patients being treated with Erivedge are also advised not to donate blood or blood products during the duration of their treatment and for atleast 7 months after the last dosage of Erivedge.
Slide 14 : Safety Advise The fact behind the excretion of vismodegib through human breast milk is not known. However, many drugs are excreted in human milk while breast-feeding. Thus, taking into account the potential of Erivedge of having serious adverse reactions, there is a requirement to decide upon the discontinuation of either nursing or the drug, depending upon the importance of the drug for the mother.
Slide 15 : Adverse Reactions Muscle spasms, alopecia, dysgeusia, weight loss, fatigue, nausea, diarrhea, decreased appetite, constipation, arthralgias, vomiting, and ageusia are the most common adverse reactions of Erivedge.
Slide 16 : Adverse Reactions Amenorrhea has been observed as an adverse effect of Erivedge during clinical trials of females of reproductive potential. As the data suggests, a total of 3 of 10 premenopausal women developed amenorrhea while receiving treatment through Erivedge during the clinical trials.

 


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