Surgical antibiotic prophylaxis
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Slide 1 :
Surgical Antibiotic Prophylaxis in a Turkish University Hospital (J. Chemotherapy, 2002;14 (4): 373-7) Prof.Dr.A.N.Yalcin* Prof.Dr.S.Serin Assoc.Prof.Dr. E.Gurses Assoc.Prof.Dr. M.Zencir
Slide 2 :
Materials and Methods Pamukkale University Hospital, Denizli, Turkey Study period: April 1st, 2001 and July 31st, 2001 Operations in general surgery, obstetrics and gynecology, orthopedics, pediatric surgery, otorhinolaryngology, plastic surgery, urology, neurosurgery, cardiothoracic surgery
Slide 3 :
Results A total of 897 operations performed in the study period. Operations: ? 70.7 % Clean surgery ? 25.3 % Clean-contaminated ? 2.8 % Contaminated ? 1.2 % Dirty
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Results (2) A total of 98 % (n:879) of all patients received antibiotic prophylaxis. Timing of prophylaxis (anesthesia induction) was appropriate ( 100 %) in all procedures. Duration of prophylaxis is appropriate in only 47.7 % of all patients. Dosages: ? 35.3 % received only one dosage. ? 12.4 % received three dosages. ? 52.3 % received prophylaxis more than a day.
Slide 5 :
Results (3) Prophylactic Antibiotics: ? Sulbactam/ampicillin (SAM): 49.5% ? Cefepime: 34 % ? Cefazolin: 9.5 % All antibiotics were administered by intravenous route.
Slide 6 :
Antibiotic choices in surgical prophylaxis Obstetrics and gynecology (n:247) Cefepime (n:247) Otorhinolaryngology (n:154) SAM (n:130), Cefazolin (n:24) General surgery (n:153) SAM (n:98), Cefazolin (n:36), Others (n:19) Urology (n:104) SAM (n:56), Cefepime (n:21), Others (n:27) Orthopedics (n:94) SAM (n:53), Cefazolin (n:16), Others (n:25) Plastic surgery (n: 55) SAM (n:48), Cefazolin (n:7) Neurosurgery (n: 40) SAM (n: 24), Cefepime (n:11), Others (n:5) Pediatric surgery (n:22) SAM (n:22) Cardiothoracic surgery (n:10) SAM (n:4), Cefepime (n:3), Others (n:3)
Slide 7 :
Discussion Unnecessary surgical antibiotic prophylaxis is higher in our study when compared with other studies. Proper duration rate is vey low in the study. Although cefazolin is recommended in surgical antibiotic prophylaxis, it is the second prefered antibiotic during the study period.
Slide 8 :
Conclusion Antimicrobial prophylaxis in surgery is not adequate in our hospital. This situation could be improved by using standardized prophylactic antibiotic administration rules. More education on the subject is a necessity.
Slide 9 :
Thanks…. firstname.lastname@example.org email@example.com
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