acute liver failure

Send This

Download

Comment

Favourite

more

Rating :

Rate It:

Embed :

Khushbu on Jul 16, 2012 Says :

nice presentation.

Post a comment

Post Comment on Twitter Post Comment on SlideWorld

Comments:

Subscribe to follow-up comments

Notes

Hide Notes

Slide 1 :

Acute Liver Failure

Slide 2 :

INTRODUCTION ACUTE LIVER FAILURE IS SUDDEN SEVERE IMPAIRMENT OF LIVER FUNCTIONS WITH COMPLICATIONS OF HEPATIC ENCEPHALOPATHY AND IMPAIRED PROTEIN SYNTHESIS. IT INDICATES THAT LIVER HAS SUSTAINED SEVERE DAMAGE[80-90% LIVER CELL FUNCTION LOSS]

Slide 3 :

AETIOLOGY ACUTE VIRAL HEPATITIS[A,B,D] DRUGS- PARACETAMOL,HALOTHANE,ANTI TB DRUGS POISONS-AMANITA [MUSHROOM] EXCESSIVE ALCOHOL INTAKE MISCELLANEOUS-WILSON DISEASE,ACUTE FATTY LIVER OF PREGNANCY,REYE’S SYNDROME IN CHILDRENS SHOCK AND CARDIAC FAILURE

Slide 4 :

BASED ON TIME TAKEN FROM JAUNDICE TO DEVELOPMENT OF HEPATIC ENCEPHALOPATHY ACUTE LIVER FAILURE CLASSIFIED AS 1.HYPERACUTE [WITHIN 1 WEEK] 2.ACUTE [8-28 DAYS] 3.SUBACUTE [4-12 WEEKS]

Slide 5 :

PATHOLOGY WIDE SPREAD HEPATOCELLULAR NECROSIS BEGINING IN CENTRIZONAL DISTRIBUTION PROGESSING TOWARDS PORTAL TRACTS

Slide 6 :

Signs and Symptoms 1.CEREBRAL DISTURBANCES[HEPATIC ENCEPHALOPATHY] 2.CEREBRAL OEDEMA-increased intracranial tension,fixed pupil,papillodema,hypertensive episodes,profuse sweating. 3.JAUNDICE 4.COAUGULOPATHY-IMPAIRED SYNTHESIS OF COAGULATION FACTORS[PROLONG PROTHROMBIN TIME]. 5.Renal failure-in about 50% patients with liver failure. 6.Fetor hepaticus 7.asterixis[flapping tremor]

Slide 7 :

More Signs and Symptoms Right hypochodrial pain Nausea ,vomiting,malaise. Local or general myoclonus,focal fits,decerebrate posturing. Ascites and oedema are late symptoms

Slide 8 :

INVESTIGATIONS Toxicologyscreening of blood &urine. Prothrombin time prolongation Complete blood picture Viral hepatitis serology IgM anti-Hbc,IgM anti HAV.ANTI HEV &HEC. AUTOIMMUNE MARKERS-ANF ,ASMA,LKM. ULTRASOUND LIVER AND DOPPLER HEPATIC VEINS.

Slide 9 :

TREATMENT IMMEADIATE ADMISSION TO ICU. SUPPORTIVE RX WITH ADEQUATE NUTRITION MAINTAINANCE OF FLUID BALANCE MECHANICAL VENTILATION INTRACRANIAL TENSION MONITORING IN SEVERE ENCEPHALOPATHY

Slide 10 :

TREATMENT CONTD… N ACETYL CYSTEINE THERAPY FOR PARACETAMOL POISOINING LIVER TRANSPLANTATION

Slide 11 :

CRITERIA FOR LIVER TRASPLANTATION FOR PATIENTS WITH PARACETAMOL TOXICITY- 1.pH<7.3 or 2 .PT >100 sec 3. serum creatinine levels-3.4 mg/dl 4.grade 3 or 4 encephalopathy

Slide 12 :

FOR OTHER PATIENTS PT>100 SEC or THREE OF THE FOLLOWING VARIABLES AGE<10 YEARS or > 40 YRS CAUSES-1.NonA NonB hepatitis 2.drug induced hepatitis 3.Duration of jaundice before encephalopathy >7 days PT>50 sec Serum bilirubin levels>17.6mg/dl

CHF Diastolic Heart ...

Management of Conges...

Acute Coronary Syndr...

Sleep Apnea and Hear...

Acute Hepatitis B Wh...

Acute Coronary Syndr...

Free Powerpoint Templates

	praneeth 10 Months ago.



513 Views, 0 favourite
PowerPoint Presentation on acute liver failure
More By User Flag as inappropriate Select your reason for flagging this presentation as inappropriate. If needed, use the feedback form to let us know more details. Cancel