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Catalytic antibodies

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Antibodies are prot...

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Antibodies are proteins (immunoglobulins) that circulate in the bloodThe best catalytic antibodies approach the worst enzymes in catalytic power (Fig. ...

3 Immunoglobulins

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Neutralization by a...

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Neutralization by antibody. Phagocytosis of antibody-antigen. complex by macrophagePolyclonal antibody; Monoclonal antibody; Engineer-based antibody ...

Immunology Adapt...

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Determines how the ...

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Determines how the antibody disposes of the bound pathogen. Fc regionOnce activated, secrete immunoglobulins as soluble antibodies. Antibodies ...

Antibodies/ Immunog...

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IgD . 1 unit. Long ...

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IgD . 1 unit. Long hinge region. Found as membrane receptor on early B cells. Not in all species.

Antigen and antibod...

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Fluorescent dyes il...

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Fluorescent dyes illuminated by ultraviolet light are used to show combination of antigen antibody .The end point antigen antibody complexes are seen ...

Snake Antivenom

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Snake antivenom and...

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Snake antivenom and anti-rabies immunoglobulins; Human blood derived products: GMP production of plasma for fractionation

PPT - 2 Artificial–...

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2 Artificial– recei...

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2 Artificial– receive antigen from vaccine or antibodies from immunoglobulins. a Active – vaccination – weakened or killed antigens immune system activated

PPT- Plasma Exchang...

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PPT- Plasma Exchang...

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PPT- Plasma Exchange or Intravenous Immunoglobulins in Treatment of ...

Endocrine Disorders...

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Graves Disease (Hyp...

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Graves Disease (Hyperthyroidism) Also known as Toxic Diffuse Goiter; Autoimmune disorder – antibodies or immunoglobulins are made and attach to thyroid stimulating hormone

Immunoglobulins Str...

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molecules that are ...

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molecules that are produced by plasma cells in response to an immunogen and which function as antibodies . Immune serum . Ag adsorbed serum ? 1 ? 2 ? ? +albumin

Dental Biochemistry...

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Transferrin, Cerulo...

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Transferrin, Ceruloplasmin. 4. Immune system Immunoglobulins,I-cell disease results from an enzyme deficiency so that lysosomal enzymes do not

PPT- Unit 5 Animal ...

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PPT- Teat ends; Ker...

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PPT- Teat ends; Keratin w/ antibacterial qualities; Immunoglobulins, lymphocytes, neutrophils; Kills mastitis through phagocytosis (engulf harmful bacteria)

Alterations in Hema...

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Bone marrow transpl...

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Bone marrow transplantation; Genetic counseling; Splenectomy .... Corticosteroids; IV immunoglobulins; Splenectomy (no response to tx 6m to 1yr) …

CITOKYNES AND IMMUN...

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MYCETOMA. 2. Mariat...

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MYCETOMA. 2. Mariat F. Bull Soc Path Exot 1963;56:35-45; López-Martínez R,MYCETOMA. 3. MYCETOMA. HOST. AGENT. ENVIROMENT. (1910-1984). (1902-1989) …

Director of Regulat...

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Hemophiliacs, needi...

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Hemophiliacs, needing clotting proteins; Immunoglobulins (IgG’s) : Immunosuppressed patients; Alpha 1 protease inhibitor : Emphesyma;

PPT- Lymphatic Syst...

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PPT- Also called im...

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PPT- Also called immunoglobulins or Igs; Gamma globulins; Location; Classes of abs; IgM; IgG; IgD; IgA; IgE; All share a basic structure, but differ functionally and in location.

X linked Hyper IgM ...

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In November 1998 a ...

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In November 1998 a younger male sibling was admitted to the ICU with severe hypoxic pneumonia; Immunoglobulins: IgM ?, IgG ?, IgA N; CD40 ligand expression on activated

PPT- heritable alle...

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PPT- heritable (all...

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PPT- heritable (allelic) variants between individuals. Km(1) vs. Km(2) G1m(1) vs. G1m(2) [b-Hb wt vs. bHbS] Variation among Immunoglobulins

Lecture 10 Immunogl...

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Whole unclotted blo...

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Whole unclotted blood: plasma (straw colored fluid-blood proteins albumin, fibrinogen, Ab) and blood cells; Whole clotted blood: serum (albumin, Ab) and clot (blood cells

The molecular genet...

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The molecular genet...

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The molecular genetics of immunoglobulins . A single C region gene encoded in the GERMLINE and separate from the V region genes; Multiple choices of V region genes

The Intravenous Imm...

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Myasthenia Gravis. ...

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Myasthenia Gravis. ? strength. 34. Multifocal neuropathy. speeds recovery. 75. Guillain Barre syndrome. IVIG for the treatment of relapsing-remitting …

Immunoglobulins Str...

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Tears, saliva, gast...

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Tears, saliva, gastric and pulmonary secretions ; Does not fix complement (unless aggregated) Binds to Fc receptors on some cells

PPT- Immunoglobulin...

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PPT- Allergen cross...

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PPT- Allergen cross-linkage of receptor-bound IgE on mast cell induces degranulation, causingrelease of substances that mediate allergic manifestations

medicine1.bjmu.edu....

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to modify immunoglo...

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to modify immunoglobulins (e.g. immunotoxins, radiolabelled antibody, bispecific antibody…It is difficult to estimate the amount of antibody to use for ...

PPT- Immunoglobulin...

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PPT- region of immu...

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PPT- region of immunoglobulin. They are also found in secretory fluids such as mucus, milkthe clearance of parasites, it has the unfortunate consequences of also causing allergy

YOUR ACTIVE IMMUNE ...

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IgA – mostly a dime...

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IgA – mostly a dimer – two Y-shaped immunoglobulins secreted in saliva, colostrum, milk, semen, mucus . IgE – binds to receptors found on mast cells – involved in allergy

ANTIBODY Ab STRUCTU...

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ANTIBODY (Ab) STRUC...

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ANTIBODY (Ab) STRUCTURE . Abs are glycoproteins of the ?-globulin class (named for electrophoretic mobility), also called immunoglobulins (Igs).

Freezing Immunoglob...

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Formation of the en...

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Formation of the encounter complex: cooperativity vs anticooperativity in the overall rate; Binding of large antigens: cooperativity of the two Fab arms

Development of B ly...

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9-year old boy, nor...

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9-year old boy, normal height and weight; Recurrent UR infections and pneumonia since 10 months of age; Physician noted absence of visible tonsils; Serum immunoglobulins:

Ai/E10 Ultra

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Role of Colostrum i...

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Role of Colostrum in Immunity . Newborn babies receive antibodies from colostrumFunctional immunoglobulins; Active immediately; Assists naturally produced



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